Mitochondrial Disorders Treatment Market Global Industry Insights, Trends, Outlook, and Opportunity Analysis, 2022-2028
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Mitochondrial Disorders Treatment Market
Mitochondrial disorders are a
group of genetic diseases that are caused by mutations in the mitochondrial DNA
(mtDNA) or nuclear DNA (nDNA) that affect the functioning of the mitochondria.
Mitochondria are organelles found in every cell in the body that are
responsible for producing energy in the form of ATP (adenosine triphosphate).
When mitochondria do not function properly, they can cause a variety of
symptoms such as muscle weakness, neurological problems, developmental delays,
and organ failure. There are currently no cures for mitochondrial disorders,
but there are treatments available that can help manage symptoms and improve
quality of life.
The Mitochondrial
Disorders Treatment Market is expected to grow
significantly over the next few years, driven by increasing awareness of these
disorders, advancements in diagnostic techniques, and the development of novel
therapeutics. The market was valued at approximately $497.4 million in 2016 and
is projected to reach $773.7 million by 2025, with a compound annual growth
rate (CAGR) of 5.1%.
One of the main treatments for
mitochondrial disorders is supportive care, which includes measures such as
physical therapy, occupational therapy, and nutritional support. These
treatments aim to manage symptoms and improve quality of life for patients. In
addition to supportive care, there are also several drugs that have been
approved by regulatory agencies for the treatment of mitochondrial disorders.
One such drug is EPI-743, which
was approved by the US Food and Drug Administration (FDA) in 2019 for the
treatment of Leigh syndrome, a severe form of mitochondrial disease that
affects the central nervous system. EPI-743 is a synthetic form of a naturally
occurring compound called coenzyme Q10 (CoQ10), which plays a key role in the
mitochondrial respiratory chain. EPI-743 has been shown to improve the
functioning of the respiratory chain and reduce oxidative stress in cells,
leading to improvements in neurological symptoms in patients with Leigh
syndrome.
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